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INA B4 Bearing Mice receiving 0.003 mg unlabeled B4 per mouse had a median survival time of 57 days. The mice receiving a single injection of [225 Ac]DOTA-B4 showed dose-related increases in median survival times 165 (6.3 kBq), 137 (4.3 kBq), and 99 days (2.1 kBq), respectively. This dose response of [225 Ac]B4 was significant with P = 0.05. 
Title Description
Realizing the potential of the Actinium-225 radionuclide ... Mice receiving 0.003 mg unlabeled B4 per mouse had a median survival time of 57 days. The mice receiving a single injection of [225 Ac]DOTA-B4 showed dose-related increases in median survival times 165 (6.3 kBq), 137 (4.3 kBq), and 99 days (2.1 kBq), respectively. This dose response of [225 Ac]B4 was significant with P = 0.05.
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